Rated 5.00 out of 5 based on 5 customer ratings
(5 customer reviews)




Opana ER is an opioid pain medication, sometimes called a narcotic.

Opana ER is used to treat moderate to severe pain.

The extended-release form of Opana ER is for around-the-clock treatment of pain. This form of oxymorphone is not for use on an as-needed basis for pain.

Opana ER may also be used for purposes not listed in this medication guide.

Important Information

You should not use this medicine if you have severe asthma or breathing problems, a blockage in your stomach or intestines, or moderate to severe liver disease.

Opana ER can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

Before taking this medicine

You should not take Opana ER if you are allergic to Opana ER, or if you have:

  • severe asthma or breathing problems;
  • a blockage in your stomach or intestines; or
  • moderate to severe liver disease.

To make sure Opana ER is safe for you, tell your doctor if you have ever had:

  • any type of breathing problem or lung disease;
  • head injurybrain tumor, or seizures;
  • drug or alcohol addiction, or mental illness;
  • urination problems;
  • liver or kidney problems; or
  • problems with your gallbladder, pancreas, or thyroid.

Some medicines can interact with Opana ER and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson’s diseasemigraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

Additional information

Weight 3 oz

5 reviews for OPANA ER 40MG

  1. Rated 5 out of 5


    “Had great analgesia with OPANA 40mg q 12 hrs.gradually upward over three year period

  2. Rated 5 out of 5


    “I was switched to Opana ER after OxyContin stopped working for my chronic nerve pain. Opana ER gave me at least 12 hrs of relief, no high, and I took much less breakthrough meds. When I went to refilll it a few months ago I was told Opana ER is no longer available due to complications addicts are getting from injecting it. I am very annoyed that the FDA prioritizes abusers over legitimate, responsible pain patients.”

  3. Rated 5 out of 5


    “I have been on Opana Er 40mg 3x a day for over a year now for chronic back pain. It is wonderful. Nothing has ever worked for me like it has. Not fentanyl patches, not oxys, nothing. I suggest any of you have a genetic test done by your pain doctor. I did. It allows your doctor to be able to tell what pain meds work for you the best. It isn’t always about what med is the strongest, its about what your body will use.”

  4. Rated 5 out of 5


    Changed my life! I was on norco for 10+ yrs and it stopped working. I started the generic Opana and it makes my pain tolerable. I’m not sure but I am retaining a lot of fluid. This is the only thing I am concerned about.”

  5. Rated 5 out of 5

    Jane Nita

    “Very effective as I can’t use NSAIDS and am allergic to many other drugs.”

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